Title : ERK crosstalks with 4EBP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.

Pub. Date : 2011 Nov

PMID : 21813464






2 Functional Relationships(s)
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1 Western blot analysis of kidney tumors formed following treatment of Tsc-2(EK/+) rats with TGHQ for 8 months revealed increases in B-Raf, Raf-1, pERK, cyclin D1, 4EBP1, and p-4EBP1-Ser65, -Thr70, and -Thr37/46 expression. 2,3,5-(triglutathion-S-yl)hydroquinone eukaryotic translation initiation factor 4E binding protein 1 Rattus norvegicus
2 Western blot analysis of kidney tumors formed following treatment of Tsc-2(EK/+) rats with TGHQ for 8 months revealed increases in B-Raf, Raf-1, pERK, cyclin D1, 4EBP1, and p-4EBP1-Ser65, -Thr70, and -Thr37/46 expression. 2,3,5-(triglutathion-S-yl)hydroquinone eukaryotic translation initiation factor 4E binding protein 1 Rattus norvegicus