Pub. Date : 2011 Oct 1
PMID : 21810437
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Involvement of phorbol-12-myristate-13-acetate-induced protein 1 in goniothalamin-induced TP53-dependent and -independent apoptosis in hepatocellular carcinoma-derived cells. | goniothalamin | tumor protein p53 | Homo sapiens |
2 | The objective was to investigate the upstream apoptotic mechanisms that were triggered by a styrylpyrone derivative, goniothalamin (GTN), in tumor protein p53 (TP53)-positive and -negative hepatocellular carcinoma (HCC)-derived cells. | goniothalamin | tumor protein p53 | Homo sapiens |
3 | The objective was to investigate the upstream apoptotic mechanisms that were triggered by a styrylpyrone derivative, goniothalamin (GTN), in tumor protein p53 (TP53)-positive and -negative hepatocellular carcinoma (HCC)-derived cells. | goniothalamin | tumor protein p53 | Homo sapiens |
4 | The objective was to investigate the upstream apoptotic mechanisms that were triggered by a styrylpyrone derivative, goniothalamin (GTN), in tumor protein p53 (TP53)-positive and -negative hepatocellular carcinoma (HCC)-derived cells. | goniothalamin | tumor protein p53 | Homo sapiens |
5 | The objective was to investigate the upstream apoptotic mechanisms that were triggered by a styrylpyrone derivative, goniothalamin (GTN), in tumor protein p53 (TP53)-positive and -negative hepatocellular carcinoma (HCC)-derived cells. | goniothalamin | tumor protein p53 | Homo sapiens |
6 | Results indicated that GTN triggered phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1, also known as NOXA)-mediated apoptosis via TP53-dependent and -independent pathways. | goniothalamin | tumor protein p53 | Homo sapiens |
7 | In TP53-positive SK-Hep1 cells, GTN furthermore induced TP53 transcription-dependent and -independent apoptosis. | goniothalamin | tumor protein p53 | Homo sapiens |
8 | In TP53-positive SK-Hep1 cells, GTN furthermore induced TP53 transcription-dependent and -independent apoptosis. | goniothalamin | tumor protein p53 | Homo sapiens |