Title : Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum Cā‚ā‚ˆ-ceramide as a novel biomarker for monitoring response.

Pub. Date : 2011 Sep 15

PMID : 21791630






1 Functional Relationships(s)
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1 Remarkably, serum sphingolipid analysis revealed significant differences in patterns of C18-ceramide elevation in patients with CR/PR/SD in comparison with patients with PD, indicating the reconstitution of tumor suppressor ceramide generation by GEM/DOX treatment. Sphingolipids Bardet-Biedl syndrome 9 Homo sapiens