Title : A novel cyclic AMP/Epac1/CaMKI signaling cascade promotes GCM1 desumoylation and placental cell fusion.

Pub. Date : 2011 Sep

PMID : 21791615






1 Functional Relationships(s)
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1 Using RNA interference (RNAi), we further demonstrate that 8-(4-chlorophenylthio)-2"-O-Me-cAMP-AM (8-CPT-AM), an Epac activator, stimulates syncytin-1 and -2 gene expression and cell fusion of placental BeWo cells in a GCM1-dependent manner. 8-(4-chlorophenylthio)-2'-O-methyl-cAMP acetoxymethyl ester glial cells missing transcription factor 1 Homo sapiens