Pub. Date : 2011 Sep
PMID : 21778880
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RECENT FINDINGS: TF contains a solvent-exposed allosteric disulfide bond that stabilizes the carboxyl-terminal domain involved in ligand interactions with coagulation factors VIIa and X. | Disulfides | coagulation factor III, tissue factor | Homo sapiens |
| 2 | PDI is a prime candidate to modify the allosteric disulfide by reduction, S-nitrosylation and glutathionation, implicated as regulators of TF procoagulant activity. | Disulfides | coagulation factor III, tissue factor | Homo sapiens |