Title : Effect of exogenous fatty acids on lipid synthesis, marker-enzymes, and development of glial cells maintained in serum-free culture.

Pub. Date : 1990

PMID : 2176647






1 Functional Relationships(s)
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1 Results show that 1) long-chain fatty acids depress the synthesis of fatty acids, cholesterol, and sulphatide; and 2) the presence of long-chain, in contrast to short-chain, fatty acids in the culture medium lowers the activities of 2",3"-cyclic-nucleotide 3"-phosphodiesterase and glycerol 3-phosphate dehydrogenase and decreases the number of oligodendrocytes. Fatty Acids 2',3'-cyclic nucleotide 3' phosphodiesterase Rattus norvegicus