Title : Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation.

Pub. Date : 2011 Jul 12

PMID : 21750559






1 Functional Relationships(s)
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Protein Name
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1 Gossypol, a small-molecule inhibitor of Bcl-2 family members, mimics the activity of quercetin by lowering Mcl-1 expression and sensitising U-937 cells to apoptosis induced by recombinant TRAIL and the Fas-ligand. Gossypol TNF superfamily member 10 Homo sapiens