Title : Carbachol mimics phorbol esters in its ability to enhance cyclic GMP production by STa, the heat-stable toxin of Escherichia coli.

Pub. Date : 1990 Nov 12

PMID : 2174803






1 Functional Relationships(s)
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1 In the present report we demonstrate that the acetylcholine analog carbachol enhanced toxin-stimulated cyclic GMP accumulation in intact T84 cells by 50-100% and that this effect was blocked by 10 microM atropine and 10 microM sphingosine. Acetylcholine 5'-nucleotidase, cytosolic II Homo sapiens