Title : Interleukin-1 synergy with phosphoinositide pathway agonists for induction of interleukin-2 gene expression: molecular basis of costimulation.

Pub. Date : 1990 Dec

PMID : 2174106






1 Functional Relationships(s)
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1 In the murine thymoma EL4.E1, IL-1 could synergize with the phosphoinositide pathway, because the cells made higher levels of IL-2 in the presence of IL-1 than could be induced by phorbol ester plus calcium ionophore alone. Calcium interleukin 1 complex Mus musculus