Title : An acetylation-mono-ubiquitination switch on lysine 120 of H2B.

Pub. Date : 2011 May

PMID : 21739721






3 Functional Relationships(s)
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1 An acetylation-mono-ubiquitination switch on lysine 120 of H2B. Lysine H2B clustered histone 21 Homo sapiens
2 Lysine 120 of H2B is modified by two PTMs: ubiquitination, which is required for further trans-tail H3 methylations and elongation, and acetylation, whose role is less clear. Lysine H2B clustered histone 21 Homo sapiens
3 Our data point at acetylation of Lysine 120 of H2B as an early mark of poised or active state and establish a temporal sequence between acetylation and mono-ubiquitination of this H2B residue. Lysine H2B clustered histone 21 Homo sapiens