Title : Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats.

Pub. Date : 2011 Nov 3

PMID : 21730356






5 Functional Relationships(s)
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1 This reticuloendothelial iron sequestration is primarily mediated by excess levels of the iron regulatory peptide hepcidin down-regulating the functional expression of the only known cellular iron export protein ferroportin resulting in blockade of iron egress from these cells. Iron hepcidin antimicrobial peptide Rattus norvegicus
2 This reticuloendothelial iron sequestration is primarily mediated by excess levels of the iron regulatory peptide hepcidin down-regulating the functional expression of the only known cellular iron export protein ferroportin resulting in blockade of iron egress from these cells. Iron hepcidin antimicrobial peptide Rattus norvegicus
3 This reticuloendothelial iron sequestration is primarily mediated by excess levels of the iron regulatory peptide hepcidin down-regulating the functional expression of the only known cellular iron export protein ferroportin resulting in blockade of iron egress from these cells. Iron hepcidin antimicrobial peptide Rattus norvegicus
4 This reticuloendothelial iron sequestration is primarily mediated by excess levels of the iron regulatory peptide hepcidin down-regulating the functional expression of the only known cellular iron export protein ferroportin resulting in blockade of iron egress from these cells. Iron hepcidin antimicrobial peptide Rattus norvegicus
5 Pharmacologic inhibition of hepcidin expression results in mobilization of iron from the RES, stimulation of erythropoiesis and correction of anemia. Iron hepcidin antimicrobial peptide Rattus norvegicus