Title : HI 6 human serum albumin nanoparticles--development and transport over an in vitro blood-brain barrier model.

Pub. Date : 2011 Sep 25

PMID : 21726608






3 Functional Relationships(s)
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1 The standard treatment of intoxication with organophosphorus (OP) compounds includes the administration of oximes acting as acetylcholinesterase (AChE) reactivating antidotes. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The standard treatment of intoxication with organophosphorus (OP) compounds includes the administration of oximes acting as acetylcholinesterase (AChE) reactivating antidotes. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
3 In vitro testing of the nanoparticulate oxime formulations in primary porcine brain capillary endothelial cells (pBCEC) demonstrated an up to two times higher reactivation of OP-inhibited AChE than the free oximes. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens