Title : The cardiac sodium channel is post-translationally modified by arginine methylation.

Pub. Date : 2011 Aug 5

PMID : 21726068






3 Functional Relationships(s)
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1 We report the identification of arginine methylation as a novel post-translational modification of Na(v)1.5. Arginine immunoglobulin lambda variable 2-18 Homo sapiens
2 The functional relevance of arginine methylation in Na(v)1.5 is underscored by the fact that R526H and R680H are known Na(v)1.5 mutations causing Brugada and long QT type 3 syndromes, respectively. Arginine immunoglobulin lambda variable 2-18 Homo sapiens
3 The functional relevance of arginine methylation in Na(v)1.5 is underscored by the fact that R526H and R680H are known Na(v)1.5 mutations causing Brugada and long QT type 3 syndromes, respectively. Arginine immunoglobulin lambda variable 2-18 Homo sapiens