Title : Further evidence for the implication of a kappa-opioid receptor mechanism in the production of psychological stress-induced analgesia.

Pub. Date : 1990 Aug

PMID : 2170723






1 Functional Relationships(s)
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1 The analgesic effect induced by exposure to psychological stress, using a communication box (psychological stress-induced analgesia, PSY-SIA), was completely antagonized by 10 min pretreatment with 0.5, 1 and 2 mg/kg of nor-binaltorphimine and with 0.5 and 1 mg/kg of Mr2266, selective kappa-opioid receptor antagonists, in the tail pinch method. norbinaltorphimine opioid receptor kappa 1 Homo sapiens