Title : GABP transcription factor is required for myeloid differentiation, in part, through its control of Gfi-1 expression.

Pub. Date : 2011 Aug 25

PMID : 21705494






3 Functional Relationships(s)
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Protein Name
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1 Gabp bound and activated the Gfi1 promoter, and transduction of Gabpa knockout bone marrow with Gfi1 partially rescued defects in myeloid colony formation and myeloid differentiation. gabp growth factor independent 1 transcription repressor Mus musculus
2 Gabp bound and activated the Gfi1 promoter, and transduction of Gabpa knockout bone marrow with Gfi1 partially rescued defects in myeloid colony formation and myeloid differentiation. gabp growth factor independent 1 transcription repressor Mus musculus
3 We conclude that Gabp is required for myeloid differentiation due, in part, to its regulation of the tran-scriptional repressor Gfi-1. gabp growth factor independent 1 transcription repressor Mus musculus