Pub. Date : 2012 Jan
PMID : 21704731
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Retinoic acid is generated from retinaldehyde in adipose tissue by the aldehyde dehydrogenase-1 family of enzymes (Aldh1). | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |
| 2 | In this review, we discuss the role of Aldh1 enzymes in the generation of retinoic acid during adipogenesis, in the regulation of the transcriptional network of PPARgamma in a fat-depot-specific manner, and the important contribution of this autocrine pathway in the development of visceral obesity. | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |