Title : Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.

Pub. Date : 2011

PMID : 21694768






1 Functional Relationships(s)
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1 We further observed decreased phosphorylation of AKT, ERK1/2 and PP1, and increased phosphorylation of p38 and JNK, suggesting that amiloride treatment down-regulates kinases and up-regulates phosphatases in the signal pathways known to affect splicing factor protein phosphorylation. Amiloride AKT serine/threonine kinase 1 Homo sapiens