Title : Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells.

Pub. Date : 2011 Sep 15

PMID : 21685203






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In this fatal lysosomal storage disease, defective alpha-N-acetylglucosaminidase interrupts the degradation of heparan sulfate (HS) proteoglycans and induces cell disorders predominating in the central nervous system, causing relentless progression toward severe mental retardation. Heparitin Sulfate N-acetyl-alpha-glucosaminidase Homo sapiens
2 In this fatal lysosomal storage disease, defective alpha-N-acetylglucosaminidase interrupts the degradation of heparan sulfate (HS) proteoglycans and induces cell disorders predominating in the central nervous system, causing relentless progression toward severe mental retardation. Heparitin Sulfate N-acetyl-alpha-glucosaminidase Homo sapiens