Title : Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice.

Pub. Date : 2011 Aug

PMID : 21673098






2 Functional Relationships(s)
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1 The glucoregulatory action of sitagliptin was associated with increased vagus nerve activity and was diminished in wild-type mice treated with the GLP-1R antagonist exendin (9-39) and in Glp1r(-/-) and Gipr(-/-) mice. Sitagliptin Phosphate glucagon-like peptide 1 receptor Mus musculus
2 The glucoregulatory action of sitagliptin was associated with increased vagus nerve activity and was diminished in wild-type mice treated with the GLP-1R antagonist exendin (9-39) and in Glp1r(-/-) and Gipr(-/-) mice. Sitagliptin Phosphate glucagon-like peptide 1 receptor Mus musculus