Title : TRPV1 activation is not an all-or-none event: TRPV1 partial agonism/antagonism and its regulatory modulation.

Pub. Date : 2011

PMID : 21671879






2 Functional Relationships(s)
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1 The identification of resiniferatoxin as an ultrapotent ligand partially able to dissect the acute activation of TRPV1 from subsequent desensitization and the subsequent intense efforts in medicinal chemistry have revealed that TRPV1 affords a dramatic landscape of opportunities for pharmacological manipulation. resiniferatoxin transient receptor potential cation channel subfamily V member 1 Homo sapiens
2 The identification of resiniferatoxin as an ultrapotent ligand partially able to dissect the acute activation of TRPV1 from subsequent desensitization and the subsequent intense efforts in medicinal chemistry have revealed that TRPV1 affords a dramatic landscape of opportunities for pharmacological manipulation. resiniferatoxin transient receptor potential cation channel subfamily V member 1 Homo sapiens