Title : Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.

Pub. Date : 2011 Jul

PMID : 21670503






1 Functional Relationships(s)
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1 These results identify PDE4B in the CaV1.2 complex as a critical regulator of ICa,L during beta-AR stimulation and suggest that distinct PDE4 subtypes are important for normal regulation of Ca2+-induced Ca2+ release in cardiomyocytes. isocyanic acid phosphodiesterase 4B, cAMP specific Mus musculus