Title : Intracellular zinc release-activated ERK-dependent GSK-3β-p53 and Noxa-Mcl-1 signaling are both involved in cardiac ischemic-reperfusion injury.

Pub. Date : 2011 Oct

PMID : 21660051






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Silencing of GSK-3beta or p53 expression was cardioprotective, indicating that activation of the ERK-GSK-3beta-p53 signaling pathway is involved in Zn(2+)-sensitive myocyte death. Zinc tumor protein p53 Homo sapiens
2 Silencing of GSK-3beta or p53 expression was cardioprotective, indicating that activation of the ERK-GSK-3beta-p53 signaling pathway is involved in Zn(2+)-sensitive myocyte death. Zinc tumor protein p53 Homo sapiens