Pub. Date : 2011 Jun
PMID : 21656050
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In addition to its principal toxic mechanisms involving iron and redox reactions, recent studies have described new mechanisms of doxorubicin-induced cell death, including abnormal protein processing, hyper-activated innate immune responses, inhibition of neuregulin-1 (NRG1)/ErbB(HER) signalling, impaired progenitor cell renewal/cardiac repair, and decreased vasculogenesis. | Doxorubicin | neuregulin 1 | Homo sapiens |
2 | In addition to its principal toxic mechanisms involving iron and redox reactions, recent studies have described new mechanisms of doxorubicin-induced cell death, including abnormal protein processing, hyper-activated innate immune responses, inhibition of neuregulin-1 (NRG1)/ErbB(HER) signalling, impaired progenitor cell renewal/cardiac repair, and decreased vasculogenesis. | Doxorubicin | neuregulin 1 | Homo sapiens |