Title : Resveratrol ameliorates muscular pathology in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.

Pub. Date : 2011 Sep

PMID : 21652783






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Resveratrol also reduced the number of alpha-smooth muscle actin (alpha-SMA)(+) myofibroblast cells and endomysial fibrosis in the biceps femoris, although the infiltration of CD45(+) inflammatory cells and increase in transforming growth factor-beta1 (TGF-beta1) were still observed. Resveratrol actin alpha 2, smooth muscle, aorta Mus musculus
2 Resveratrol also reduced the number of alpha-smooth muscle actin (alpha-SMA)(+) myofibroblast cells and endomysial fibrosis in the biceps femoris, although the infiltration of CD45(+) inflammatory cells and increase in transforming growth factor-beta1 (TGF-beta1) were still observed. Resveratrol actin alpha 2, smooth muscle, aorta Mus musculus
3 In C2C12 myoblast cells, resveratrol pretreatment suppressed the TGF-beta1-induced increase in reactive oxygen species, fibronectin production, and expression of alpha-SMA, and SIRT1 knockdown blocked these inhibitory effects. Resveratrol actin alpha 2, smooth muscle, aorta Mus musculus