Title : Endothelial angiotensin-converting enzyme and neutral endopeptidase in isolated human umbilical vein: an effective bradykinin inactivation pathway.

Pub. Date : 2011 Sep 30

PMID : 21651905






1 Functional Relationships(s)
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1 Application of captopril 1 muM (angiotensin-converting enzyme inhibitor) or phosphoramidon 10 muM (neutral endopeptidase inhibitor) induced a leftward shift of bradykinin-elicited responses in human umbilical vein with endothelium while no effect was observed in tissues denuded of endothelium under the same treatment. Captopril kininogen 1 Homo sapiens