Title : siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice.

Pub. Date : 2011 Oct

PMID : 21638135






1 Functional Relationships(s)
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1 The P-gp down-regulation by intratumoral siRNA injection led to better response to systemic Doxil treatment, resulting in slowed tumor growth in originally doxorubicin-resistant tumors. liposomal doxorubicin phosphoglycolate phosphatase Mus musculus