Pub. Date : 2012 Aug
PMID : 21633925
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the present study, we show that retinoic acid enhances the cytostatic and apoptogenic properties of the novel adamantyl retinoid ST1926 in a panel of neuroblastoma cells with different p53 status and caspase 8 expression, resulting in synergistic effects as assessed by Combination Index and Isobologram analysis. | Tretinoin | tumor protein p53 | Homo sapiens |
2 | Although not modulated, p53 appeared to enhance cells responsiveness to retinoid/ATRA combination. | Tretinoin | tumor protein p53 | Homo sapiens |