Pub. Date : 2011
PMID : 21628880
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TBMS I induced cell shrinkage, nuclear condensation and fragmentation, cell cycle arrest at the G2/M phase, mitochondrial membrane disruption, release of cytochrome c from the mitochondria, activation of caspase 3 and 9, and shifting Bax/Bcl-2 ratio from being anti-apoptotic to pro-apoptotic, all indicative of initiation and progression of apoptosis involving mitochondrial dysfunction. | tubeimoside I | caspase 3 | Homo sapiens |