Title : MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells to facilitate cytotoxic T lymphocyte-mediated tumor cell killing.

Pub. Date : 2011 Sep

PMID : 21626030






4 Functional Relationships(s)
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1 We have demonstrated that the expression of MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells following exposure to pharmacologic levels of the demethylating agent 5-aza-2"-deoxycytidine (decitabine, DAC). Decitabine MAGE family member A3 Homo sapiens
2 We have demonstrated that the expression of MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells following exposure to pharmacologic levels of the demethylating agent 5-aza-2"-deoxycytidine (decitabine, DAC). Decitabine MAGE family member A3 Homo sapiens
3 We have demonstrated that the expression of MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells following exposure to pharmacologic levels of the demethylating agent 5-aza-2"-deoxycytidine (decitabine, DAC). Decitabine MAGE family member A3 Homo sapiens
4 Expression of NY-ESO-1, MAGE-A1, or MAGE-A3 was induced in 10/10 neuroblastoma cell lines after 5 days of exposure to DAC. Decitabine MAGE family member A3 Homo sapiens