Pub. Date : 2011 Aug
PMID : 21617855
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that caffeine induced increased intracellular cAMP levels, PTEN activation and Akt inactivation, which together prevented proliferation of human osteosarcoma cells (MG63) and fibrosarcoma cells (HT1080). | Caffeine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | PTEN knockdown by siRNA reduced the effects of caffeine on Akt inactivation in osteosarcoma cells. | Caffeine | AKT serine/threonine kinase 1 | Homo sapiens |