Title : Roles of organic anion/cation transporters at the blood-brain and blood-cerebrospinal fluid barriers involving uremic toxins.

Pub. Date : 2011 Aug

PMID : 21611756






1 Functional Relationships(s)
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1 Our recent research provides novel molecular and functional evidence that indoxyl sulfate, an anionic uremic toxin, undergoes efflux transport at the BBB via OAT3 and creatinine, a uremic guanidino compound, undergoes efflux transport at the BCSFB via OCT3. Creatinine solute carrier family 22 member 3 Homo sapiens