Title : Differential reduction of HCN channel activity by various types of lipopolysaccharide.

Pub. Date : 2011 Aug

PMID : 21609720






1 Functional Relationships(s)
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1 We evaluated the effect of various types of LPS on the activity of human hyperpolarization-activated cyclic nucleotide-gated channel 2 (hHCN2) expressed in HEK293 cells, and on pacemaker channels in native murine sino-atrial node (SAN) cells, in order to determine the structure of LPS necessary to modulate pacemaker channel function. Nucleotides, Cyclic hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 Homo sapiens