Title : Control of arterial pressure and renal function during chronic renin inhibition.

Pub. Date : 1990 Apr

PMID : 2160492






3 Functional Relationships(s)
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1 The aim of this study was to determine whether the renin inhibitor CP-71362 (Pfizer Central Research, Groton, Connecticut, USA) is capable of inducing sustained reductions in arterial pressure in sodium-depleted dogs and to examine the changes in renal function associated with chronic renin inhibition. CP 71362 renin Canis lupus familiaris
2 The aim of this study was to determine whether the renin inhibitor CP-71362 (Pfizer Central Research, Groton, Connecticut, USA) is capable of inducing sustained reductions in arterial pressure in sodium-depleted dogs and to examine the changes in renal function associated with chronic renin inhibition. CP 71362 renin Canis lupus familiaris
3 Plasma renin activity was suppressed to undetectable levels throughout the 7 days of CP-71362 infusion. CP 71362 renin Canis lupus familiaris