Title : HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.

Pub. Date : 2011 Dec 1

PMID : 21602882






1 Functional Relationships(s)
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1 Phosphorylation of p53 at S46, an apoptosis-specific p53 posttranslational modification, is the most characterized HIPK2 function in response to lethal doses of ultraviolet (UV), ionizing radiation or different anticancer drugs, such as cisplatin, roscovitine and doxorubicin (DOX). Cisplatin homeodomain interacting protein kinase 2 Homo sapiens