Title : The first total synthesis of (±)-cyclophostin and (±)-cyclipostin P: inhibitors of the serine hydrolases acetyl cholinesterase and hormone sensitive lipase.

Pub. Date : 2011 Jun 17

PMID : 21591624






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The first total synthesis of (+-)-cyclophostin and (+-)-cyclipostin P: inhibitors of the serine hydrolases acetyl cholinesterase and hormone sensitive lipase. cyclophostin lipase E, hormone sensitive type Homo sapiens
2 The unnatural diastereomer of cyclophostin was converted into cyclipostin P, a potent naturally occurring hormone sensitive lipase (HSL) inhibitor, using a one pot dealkylation-alkylation process. cyclophostin lipase E, hormone sensitive type Homo sapiens
3 The unnatural diastereomer of cyclophostin was converted into cyclipostin P, a potent naturally occurring hormone sensitive lipase (HSL) inhibitor, using a one pot dealkylation-alkylation process. cyclophostin lipase E, hormone sensitive type Homo sapiens