Title : Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling.

Pub. Date : 2011 Jul 15

PMID : 21586278






1 Functional Relationships(s)
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1 Here, we demonstrate a highly penetrant dramatic defect in primary branching by mammary epithelial-specific inactivation of Ext1, a subunit of the copolymerase complex that catalyzes the formation of the heparan sulfate chain. Heparitin Sulfate exostosin glycosyltransferase 1 Homo sapiens