Title : Altered post-receptorial signal transduction mechanism under various stimulation in polymorphonuclear granulocytes of Alzheimer's disease.

Pub. Date : 1990 Mar 15

PMID : 2157926






1 Functional Relationships(s)
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1 The cyclic nucleotide changes were studied under 10(-6) M isoproterenol (IP), 10(-6) M carbachol and 10(-8) M Met-enkephalin (Met-enk) stimulations in polymorphonuclear granulocytes (PMNLs) of middle-aged (aged 35-52 years) and elderly (aged 61-97 years) healthy subjects, as well as of patients with Alzheimer"s disease (AD) (aged 58-65 years). Nucleotides, Cyclic proopiomelanocortin Homo sapiens