Pub. Date : 2011 Aug
PMID : 21571040
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metabolite modulation of HeLa cell response to ENOX2 inhibitors EGCG and phenoxodiol. | phenoxodiol | ecto-NOX disulfide-thiol exchanger 2 | Homo sapiens |
| 2 | CONCLUSIONS: Based on findings with metabolites, we conclude that apoptosis in cancer cell lines caused by ENOX2 inhibitors such as EGCG and phenoxodiol is a direct response to elevated levels of cytosolic NADH that result from ENOX2 inhibition. | phenoxodiol | ecto-NOX disulfide-thiol exchanger 2 | Homo sapiens |
| 3 | CONCLUSIONS: Based on findings with metabolites, we conclude that apoptosis in cancer cell lines caused by ENOX2 inhibitors such as EGCG and phenoxodiol is a direct response to elevated levels of cytosolic NADH that result from ENOX2 inhibition. | phenoxodiol | ecto-NOX disulfide-thiol exchanger 2 | Homo sapiens |