Title : NOD2 signaling contributes to the innate immune response against helper-dependent adenovirus vectors independently of MyD88 in vivo.

Pub. Date : 2011 Sep

PMID : 21561248






1 Functional Relationships(s)
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1 We now show that NOD2, a nucleotide-binding and oligomerization domain (NOD)-like receptor known to detect muramyl dipeptides in bacterial peptidoglycans, also contributes to innate responses to HDAds, but not to humoral or Th1 immune responses. Dipeptides nucleotide-binding oligomerization domain containing 2 Mus musculus