Pub. Date : 2011 Jul
PMID : 21558315
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In our experiments, human CG (hCG)/cAMP stimulation rapidly and transiently increased MKP-1 mRNA levels by a transcriptional action. | Cyclic AMP | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 2 | In cells transiently expressing flag-MKP-1 protein, hCG/cAMP promoted the accumulation of the recombinant protein in a time-dependent manner (10-fold at 1 h). | Cyclic AMP | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 3 | Moreover, hCG/cAMP triggered ERK1/2-dependent MKP-1 phosphorylation. | Cyclic AMP | hypertrichosis 2 (generalised, congenital) | Homo sapiens |