Title : Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells.

Pub. Date : 2011 Jul 1

PMID : 21557999






3 Functional Relationships(s)
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Protein Name
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1 Depletion of either thioredoxin also potentiated the toxicity produced either by a glutathione synthesis inhibitor or by TNFalpha in E47 cells. Glutathione thioredoxin Homo sapiens
2 GSH was decreased and adding GSH completely blocked E47 cell death induced by either thioredoxin knockdown. Glutathione thioredoxin Homo sapiens
3 GSH was decreased and adding GSH completely blocked E47 cell death induced by either thioredoxin knockdown. Glutathione thioredoxin Homo sapiens