Title : Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

Pub. Date : 2011 Apr

PMID : 21552545






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Similar to direct DSBs, the derived DSBs were subject to MRX (Mre11, Rad50, Xrs2)-determined resection and relied upon the recombinational repair genes RAD51, RAD52, as well as on the MCD1 cohesin gene, for repair. dsbs MRX complex DNA-binding subunit Saccharomyces cerevisiae S288C
2 Similar to direct DSBs, the derived DSBs were subject to MRX (Mre11, Rad50, Xrs2)-determined resection and relied upon the recombinational repair genes RAD51, RAD52, as well as on the MCD1 cohesin gene, for repair. dsbs MRX complex DNA-binding subunit Saccharomyces cerevisiae S288C