Title : Design and synthesis of pyrrolidine-containing sphingomimetics.

Pub. Date : 2011 Jun 21

PMID : 21537513






1 Functional Relationships(s)
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1 Based on the structures of natural sphingolipids, we designed heterocyclic sphingoid base mimetics in which the conformational restriction is introduced by incorporation of a pyrrolidine moiety between the 2-amino group and the C-4 carbon atom of the sphingoid base. Carbon complement C4A (Rodgers blood group) Homo sapiens