Title : P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism.

Pub. Date : 2011 Oct 13

PMID : 21516125






1 Functional Relationships(s)
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1 Here we demonstrate that TAp73alpha over-expression enhanced CDDP-induced PARP cleavage and apoptosis in both chemosensitive (OV2008 and A2780s) and their resistant counterparts (C13* and A2780cp) and another chemoresistant OVCA cells (Hey); in contrast, the effect of DeltaNp73alpha over-expression was variable. Cisplatin collagen type XI alpha 2 chain Homo sapiens