Title : Efficient synthesis and chiral separation of 11C-labeled ibuprofen assisted by DMSO for imaging of in vivo behavior of the individual isomers by positron emission tomography.

Pub. Date : 2011 May 15

PMID : 21515058






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1 The efficient (11)C-labeling of ibuprofen for chiral separation via the TBAF-promoted alpha-[(11)C]methylation was achieved by using DMSO rather than THF as the reaction solvent. tetrabutylammonium thin fur Mus musculus