Title : [The role of DNA double strains damage repairing mechanisms in high glucose-induced endothelial senescence].

Pub. Date : 2011 Mar

PMID : 21500551






2 Functional Relationships(s)
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1 Intra-cellular levels of gamma-H2AX and phosphorylated P53 protein were significantly increased in high glucose groups. Glucose tumor protein p53 Homo sapiens
2 ATM-P53 pathway, the key proteins related to DNA double strain damage repairing mechanisms, may play an important role in high glucose induced cellular senescence and atherosclerosis. Glucose tumor protein p53 Homo sapiens