Title : Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes.

Pub. Date : 2011 Sep

PMID : 21498084






1 Functional Relationships(s)
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1 WT+STZ mice exhibited significantly increased levels of serum and macrophage IL-1beta, IL-6, KC/IL-8, IP-10, MCP-1, IFN beta and TNF-alpha compared to WT mice and this was significantly attenuated in TLR4(-/-) +STZ mice (P<0.01). Streptozocin interleukin 1 beta Mus musculus