Title : Liquid chromatography-tandem mass spectrometry method for measurement of nicotine N-glucuronide: a marker for human UGT2B10 inhibition.

Pub. Date : 2011 Jul 15

PMID : 21497036






1 Functional Relationships(s)
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1 This established method was employed to evaluate the inhibitory effects of five target compounds including amitriptyline, hecogenin, imipramine, lamotrigine, and trifluoperazine on enzymatic activity of UGT2B10. Imipramine UDP glucuronosyltransferase family 2 member B10 Homo sapiens