Title : Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells.

Pub. Date : 2010 Oct

PMID : 21487509






1 Functional Relationships(s)
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1 We demonstrate that RA containing PLGA nanoparticles suppress IL-17 production and ROR-gamma(t) expression in T cells polarized towards the Th17 phenotype in vitro with similar potency to that of free drug. Tretinoin interleukin 17A Homo sapiens