Pub. Date : 2011 Mar-Apr
PMID : 21468572
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sulforaphane blocks hypoxia-mediated resistance to TRAIL-induced tumor cell death. | sulforaphane | TNF superfamily member 10 | Homo sapiens |
| 2 | SFN treatment enhanced TRAIL-induced activation of proteins, including caspase-3 and p53. | sulforaphane | TNF superfamily member 10 | Homo sapiens |
| 3 | This study demonstrated that SFN recovered hypoxia-mediated resistance to TRAIL via instability of HIF-1alpha, and also suggests that combination therapy with SFN and TRAIL may provide a novel strategy for treating hypoxic solid tumors. | sulforaphane | TNF superfamily member 10 | Homo sapiens |